131 Effect on Hair Growth of HEM-13/HDC Hair Tonic(Herbal Extract Mixtures) in Androgenetic Alopecia as Measured by Phototrichogram

BJ Shin, SW Ahn, WJ Tak, BI Ro. Dept. of Dermatology, College of Medicine, Chung Ang University, Seoul, Korea.

We studied to investigate the clinical improvement of herbal extract mixtures in the patients with androgenetic alopecia. Total 76 patients(treatment group: 62, placebo group: 14, male: 63, female: 13) with androgenetic alopecia received topical application of HEM-13/HDC hair tonic or placebo for 6 months and then all of them received topical application of HEM-13/HDC hair tonic for 3 months. The efficacy was evaluated by hair counts, patient self-assessment, global photographic assessment and phototrichogram of the bald area in a circle of 1cm in diameter. Hair count and image analysis was performed before treatment, at 3, 6, 9 month after treatment respectively to compare the hair shaft diameter and hair density. At baseline, mean total hair counts in the tested area were 63.4 in the treatment group and 64.7 in the placebo group. At month 6, patients in the placebo had a decrease (mean ± SE) in hair counts of 1.3 ± 0.4 hairs. At month 9, patients in the treatment had an improvement (mean ± SE) in hair counts of 3.5 ± 0.7 hairs respectively (p<0.05), and had a significant increase in hair diameter (p<0.05). These data support that HEM-13/HDC hair tonic results in favorable effects on hair growth of patients with androgentic alopecia.