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42. Hair loss
of type telogen effluvium and androgenetic alopecia in women is not correlated
to
zinc levels in the serum.
Raziel Lurie(1), Uri Ron(2), Michael David(3), Emelia Hodak(3) 1.Maccabi Healthcare
Services; Pediatric Dermatology Hair Clinic, Schneider Children's Medical Center
of Israel, 2. Department of Biochemistry, The George S. Wise Faculty of Life
Sciences, Tel Aviv University, 3.Department of Dermatology, Rabin Medical Center,
Beilinson Hospital, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Background: Medical literature as to the correlation between hair-loss and
various nutritional deficiencies in general and specifically zinc is scarce.
There is no well-based study which established that in people with no background
diseases, linked to known nutritional deficiencies, hair-loss was caused by
a Zinc deficiency. Nevertheless, the popular view is that low serum Zinc concentrations
cause hair loss, and many trichologists/dermatologists/medical doctors carry
out serum Zinc-concentration tests, and prescribe Zinc supplements as treatment
for hair-loss.
Goal: testing whether common types of hair loss in women, i.e. Telogen Effluvium
(TE), Chronic Telogen Effluvium (CTE) and Androgenetic Alopecia (AGA) are correlated
to low serum Zinc concentrations.
Methods: The study included 1459 women (mean age: 38.5 years, range: 17-89
years) who visited a dermatology clinic which specializes in the diagnosis
and treatment of hair-loss. The diagnosis was based on a full medical anamnesis
accompanied by a physical examination. 765 women were reported as suffering
from TE; 645 suffered from AGA; and 49 women suffered from CTE. In some unclear
cases the diagnosis was based upon a trichogram examination using the German
method. Serum Zinc concentrations were tested after an overnight fast and in
a single laboratory. The patients did not use nutritional supplements at least
3 months prior to the blood test.
Results: Serum Zinc concentrations measured were normal in all women (mean:
108.1 microgram/dl; the norm ranges between 55-165 microgram/dl), except for
2 women, whose serum Zinc levels were slightly under the norm (53, 54).
Conclusions: Hair-loss of types, TE, CTE and AGA in women is not linked to
low serum Zinc concentrations. Hence, in our opinion, testing for serum Zinc
levels should not be a routine examination for diagnosing hair-loss in women.
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